Bookcover of Spontaneously Hypertensive Rat
Booktitle:

Spontaneously Hypertensive Rat

Alphascript Publishing (2011-04-12 )

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ISBN-13:

978-613-5-62717-6

ISBN-10:
6135627171
EAN:
9786135627176
Book language:
English
Blurb/Shorttext:
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Spontaneously hypertensive rat (SHR) is an animal model of essential (or primary) hypertension, used to study cardiovascular disease. It is the most studied model of hypertension measured as number of publications. The SHR strain was obtained during the 1960s by Okamoto and colleagues, who started breeding Wistar-Kyoto rats with high blood pressure. The Spontaneously Hypertensive Rat (SHR) is also used as a model of attention-deficit hyperactivity disorder. If the animal is to be used as a model of ADHD, it is generally advised to start testing when the animals are around four weeks old (PND 28) before the onset of hypertension. Despite the criticisms associated with using animals to research essentially human conditions, Sagvolden supported his Dynamic Developmental Theory of ADHD using research primarily done using Spontaneously Hypertensive Rats.
Publishing house:
Alphascript Publishing
Website:
https://www.alphascript-publishing.com/
Edited by:
Frederic P. Miller, Agnes F. Vandome, John McBrewster
Number of pages:
96
Published at:
2011-04-12
Stock:
Available
Category:
Biology
Price:
34.00 €
Keywords:
rat, hypertension, Cardiovascular Disease, Animal Testing, Rating, Hypertension, Cardiovascular diseases

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