Bookcover of Role of Tribulus terrestris against acetaminophen-induced liver damage
Booktitle:

Role of Tribulus terrestris against acetaminophen-induced liver damage

The promise of Tribulus terrestris L. in liver protection: A mechanistic approach in acetaminophen-induced liver damage

LAP LAMBERT Academic Publishing (2012-10-24 )

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ISBN-13:

978-3-659-28094-8

ISBN-10:
3659280941
EAN:
9783659280948
Book language:
English
Blurb/Shorttext:
Problems related to liver such as acute or chronic inflammation, toxin-/drug-induced hepatitis, cirrhosis and hepatitis are very common today due to our exposure to different environmental pollutants like chemicals, toxins, viruses etc. For centuries, many herbs have been used as natural medications for the prevention and/or treatment of liver diseases. Thus, the aim of the present study was to evaluate the role of Tribulus terrestris Linn. on acetaminophen-induced liver damage in rats. The rats were divided into five groups of 6 rats each for seven days oral administration. The methanolic extract of Tribulus terrestris L. produced significant hepatoprotective effects as evidenced by decreased serum enzyme activities, SGOT, SGPT, ALP, serum bilirubin, increased total protein. Histopathological architecture of the liver in test group was identical to the reference group. Based on our present findings, it can be concluded that Tribulus terrestris Linn. protects the liver from acetaminophen-induced hepatic damage by stabilizing effect on the plasma membrane as was reported in the case of Silymarin. Responsible leads for the present hepatoprotective studies are flavonoids.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Javed Akhtar Ansari
Number of pages:
80
Published at:
2012-10-24
Stock:
Available
Category:
Pharmacy
Price:
53.41 $
Keywords:
liver, acetaminophen, rats, Tribulus Terrestris

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