Bookcover of REGULATORY T CELLS AND INTERLEUKIN-10
Booktitle:

REGULATORY T CELLS AND INTERLEUKIN-10

Role in Pulmonary Tuberculosis

LAP LAMBERT Academic Publishing (2011-06-23 )

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ISBN-13:

978-3-8454-0437-0

ISBN-10:
384540437X
EAN:
9783845404370
Book language:
English
Blurb/Shorttext:
Mycobacterium tuberculosis infects one-third of the world's population and causes almost 2 million deaths per year. In spite of intense research on the immune response elicited during tuberculosis, the mechanisms involved in the development of active disease remain obscure. There is growing evidence that regulatory T cells may play an important role in the regulation of host immune responses against M. tuberculosis. In some circumstances, the regulation exerted by regulatory T cells is excessive and prevents the establishment of protective immune responses, whereas in other circumstances, this control is not sufficient to prevent immunopathology. IL-10 has been described as a T helper 2 cytokine with immunosuppressive properties. In addition, IL-10 secretion has been reported as one of the mechanisms by which regulatory T cells may exert their suppressive function. This study, therefore, was conducted to determine CD4+CD25+ regulatory T cells % and the levels of IL-10 mRNA expression in peripheral blood of patients with active pulmonary tuberculosis. This should help to assess a possible role of these cells in the immunopathogenesis of TB, and should be especially useful to researc
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Marwa Nasser, Rasha Nasr, Nehal Draz
Number of pages:
112
Published at:
2011-06-23
Stock:
Available
Category:
Medicine
Price:
49.00 €
Keywords:
Regulatory T cells, interleukin10, Pulmonary Tuberculosis, regulatory T cells, pulmonary tuberculosis

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