Flap Endonuclease
978-613-3-93250-0
6133932503
104
2010-11-22
39.00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Flap endonucleases are a class of nucleolytic enzymes that act as both 5'-3' exonucleases and structure specific endonucleases on specialised DNA structures that occur during the biological processes of DNA replication, DNA repair and DNA recombination. Flap endonucleases have been identified in eukaryotes, prokaryotes, archaea and some viruses. Organisms can have more than one FEN homologue, this redundancy may give an indication of the importance of these enzymes. In prokaryotes, the FEN enzyme is found as an N-terminal domain of DNA polymerase I, but some prokaryotes appear to encode a second homologue.
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