Barr body
978-613-0-86550-4
6130865503
84
2010-06-22
34.00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. A Barr body is the inactive X chromosome in a female cell, or the inactive Z in a male, rendered inactive in a process called lyonization, in those species in which sex is determined by the presence of the Y or W chromosome rather than the diploidy of the X or Z. The Lyon hypothesis states that in cells with multiple X chromosomes, all but one are inactivated during mammalian embryogenesis. This happens early in embryonic development at random in mammals, except in marsupials and in some extra-embryonic tissues of some placental mammals, in which the father's X chromosome is always deactivated. Barr bodies are named after their discoverer, Murray Barr. In men and women with more than one X chromosome, the number of Barr bodies visible at interphase is always one less than the total number of X chromosomes. For example, men with a 47,XXY karyotype have a single Barr body, whereas women with a 47,XXX karyotype have two Barr bodies.
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