Capa do livro de Homology Modeling of Human NK-1 Receptor and Docking Study
Título do livro:

Homology Modeling of Human NK-1 Receptor and Docking Study

Structure Based Drug Design

LAP LAMBERT Academic Publishing (2015-11-16 )

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ISBN- 1 3:

978-3-659-80420-5

ISBN- 1 0:
3659804207
EAN:
9783659804205
Idioma do livro:
Inglês
Anotações e citações/ texto breve:
Neurokinin-1 (NK-1) receptor regulates many biological functions related to cancer, such as tumor cell proliferation, angiogenesis and migration of tumor cells for invasion and metastasis. The NK-1 receptor antagonists specifically inhibit tumor cell proliferation, migration of the tumor cells and show antiangiogenic effect. Therefore, the development of NK-1 antagonists for the treatment of cancer is of current interest. The 3D structure of NK-1 is not available from protein data bank. This hampers the design of selective NK-1 antagonists. This book describes the homology modeling of the human NK-1 receptor using multiple templates to provide structural basis for the design of new NK-1 inhibitors and anticancer agents. The authors anticipate that the book will be very useful for the researchers who are working on the design and development of NK-1 receptor antagonists and anticancer agents.
Editora:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
Por (autor):
Manish K. Gupta, Viney Kumar
Número de páginas:
92
Publicado em:
2015-11-16
Stock:
Disponível
Categoria:
Farmácia
Preço:
54.9 €
Palavras chave:
Cancer, Docking, Drug design, homology modeling, NK-1 receptor, Tachykinin

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