Copertina di Murine mammary gland: Expression of cytokeratin intermediate filaments
Titolo del libro:

Murine mammary gland: Expression of cytokeratin intermediate filaments

Cytokeratin expression in mouse mammary gland and review of intermediate filaments

Editorial Académica Española (10.05.2017 )

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ISBN-13:

978-3-659-65396-4

ISBN-10:
3659653969
EAN:
9783659653964
Lingua del libro:
Risvolto di copertina:
Changes during mammary gland development can be detected with methods using specific antibodies directed against specific cell structures. In the present study, the expression pattern of a type of intermediate filament called cytokeratins (CKs) was evaluated in tissue samples from mice mammary glands during the first five weeks post-partum (pp). Several CKs were analyzed with specific markers and immunohistochemistry methods. It is known that CK expression varies with physiological and pathological changes, and it has been reported to mark different epithelial cell lineages; its evaluation is therefore of considerable importance for studies of breast cancer of a stem/progenitor cell origin, both in humans and animals. Our trial provides additional knowledge relative to the use of specific antibodies and techniques as valuable tools to detect CKs during early pp mice mammary gland development (weeks 1 to 5 pp), emphasizing the role of CKs as markers of mammary epithelial differentiation.
Casa editrice:
Editorial Académica Española
Sito Web:
https://www.eae-publishing.com/
Da (autore):
José Manuel Martínez Pérez, Isabel MaurizTurrado
Numero di pagine:
64
Pubblicato il:
10.05.2017
Giacenza di magazzino:
Disponibile
categoria:
Veterinaria
Prezzo:
35,90 €
Parole chiave:
mouse, Cytokeratin, mammary gland, intermediate filaments, vimentin

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