Hartnup Disease
Amino acid, Tryptophan, Nicotinamide, Melatonin, SLC6A19
978-620-0-78514-5
6200785147
84
2012-03-01
34,00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. The defective gene controls the absorption of certain amino acids from the intestine and the reabsorption of those amino acids in the kidneys. Consequently, a person with Hartnup disease cannot absorb amino acids properly from the intestine and cannot reabsorb them properly from tubules in the kidneys. Excessive amounts of amino acids, such as tryptophan, are excreted in the urine. The body is thus left with inadequate amounts of amino acids, which are the building blocks of proteins. With too little tryptophan in the blood, the body is unable to make a sufficient amount of the B-complex vitamin niacinamide, particularly under stress when more vitamins are needed.
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Bilógia
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