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Könyv címe:

Atrial Fibrillation - Inside the Arrhythmogenic Substrate

LAP LAMBERT Academic Publishing (30.08.2013 )

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ISBN-13:

978-3-659-44978-9

ISBN-10:
3659449784
EAN:
9783659449789
Könyv nyelve:
angol
Ismertető:
Atrial fibrillation is the most prevalent form of cardiac arrhythmia. Studies in animal models have provided important insights into arrhythmia mechanisms. However, to date, we do not dispose of animal models of spontaneous atrial arrhythmia. Therefore, we sought to develop a model of spontaneous atrial arrhythmias in rats and to assess pathophysiological mechanisms of these arrhythmias by using a multidisciplinary approach. We also assessed the presence and the extent of inflammation and endothelial dysfunction, incriminated in atrial fibrillation-related complications such as stroke, in atrial fibrillation patients. This book describes the first animal model of spontaneous atrial arrhythmias and provides evidence that multiple mechanisms participate to arrhythmia occurrence in this model, particularly autonomic imbalance and left atrial endocardial fibrosis. Together with the clinical studies, this work adds new and important insights into the mechanisms of atrial arrhythmias and helps understanding the complex pathophysiological mechanisms of atrial fibrillation.
Kiadó:
LAP LAMBERT Academic Publishing
Weboldal:
https://www.lap-publishing.com/
Szerezte:
Alina Scridon, Philippe Chevalier
Oldalszám:
152
Kiadja:
30.08.2013
Raktárkészlet:
Raktáron
Kategória:
Gyógyszerészet
Ár:
61,90 €
Kulcsszavak:
Autonomic Nervous System, Endothelial Dysfunction, atrial arrhythmias, experimental model, histology, Stroke, inflammation, Fibrosis

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