A23187
Ionophore, Fermentation (biochemistry), Streptomyces, Cancer, Topotecan
978-613-5-80975-6
613580975X
64
2011-05-19
29,00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. A23187 is a mobile ion-carrier that forms stable complexes with divalent cations (ions with a charge of +2). A23187 is also known as Calcimycin, Calcium Ionophore, Antibiotic A23187 and Calcium Ionophore A23187. It is produced at fermentation of Streptomyces Chartreusensis. A23187 has antibiotic properties against gram positive bacteria and fungi. It also acts as a divalent cation ionophore, allowing these ions to cross cell membranes, which are usually impermeable to them. A23187 is most selective for Mn2+, somewhat less selective for Ca2+ and Mg2+, much less selective for Sr2+, and even less selective for Ba2+.
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Kémia
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