Bookcover of Transforming Growth Factor Beta
Booktitle:

Transforming Growth Factor Beta

Alphascript Publishing (2010-12-19 )

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ISBN-13:

978-613-4-05651-9

ISBN-10:
6134056510
EAN:
9786134056519
Book language:
English
Blurb/Shorttext:
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Transforming growth factor beta (TGF-β) is a protein that controls proliferation, cellular differentiation, and other functions in most cells. It plays a role in immunity, cancer, heart disease, diabetes, and Marfan syndrome. TGF-beta acts as an antiproliferative factor in normal epithelial cells and at early stages of oncogenesis. Some cells secrete TGF-β, and also have receptors for TGF-β. This is known as autocrine signalling. Cancerous cells increase their production of TGF-β, which also acts on surrounding cells. TGF-β is a secreted protein that exists in three isoforms called TGF-β1, TGF-β2 and TGF-β3. It was also the original name for TGF-β1, which was the founding member of this family. The TGF-β family is part of a superfamily of proteins known as the transforming growth factor beta superfamily, which includes inhibins, activin, anti-müllerian hormone, bone morphogenetic protein, decapentaplegic and Vg-1.
Publishing house:
Alphascript Publishing
Website:
https://www.alphascript-publishing.com/
Edited by:
Frederic P. Miller, Agnes F. Vandome, John McBrewster
Number of pages:
72
Published on:
2010-12-19
Stock:
Available
Category:
Medicine
Price:
29.00 €
Keywords:
Transforming, growth, factor, cellular, differentiation, Syndrome, "Factoring

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