Bookcover of Process Development of Amlodipine and Olmesartan Medoxomil Tablets
Booktitle:

Process Development of Amlodipine and Olmesartan Medoxomil Tablets

Process Development of Amlodipine and Olmesartan Medoxomil Tablets 10/40 Mg

LAP LAMBERT Academic Publishing (2021-02-08 )

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ISBN-13:

978-620-3-40933-8

ISBN-10:
6203409332
EAN:
9786203409338
Book language:
English
Blurb/Shorttext:
The present study was focused on process development of amlodipine and olmesartan medoxomil tablet 10/40mg. Amlodipine and Olmesartan medoxomil is a combination of a calcium channel blocker and an angiotensin II receptor antagonist used to treat high blood pressure . The Content uniformity was found of both the drugs were performed. Release study was conducted in pH 6.8 buffer media. Furthermore, dissolution profile comparison was carried out using similarity factor (f2) and the similarity factor of Amlodipine and Olmesartan Medoxomil found to be 73. Other studies Like DSC and FTIR studies reported compatibility of Amlodipine besylate with excipients like Cross Carmel lose sodium was performed shows no chemical interaction between drug and excipients. Dissolution profile of Test and Reference standard found to be similar, Similarity factor (f2) is 73.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Gayatri Behera, Jayashree Behera, Binapani Barik
Number of pages:
72
Published on:
2021-02-08
Stock:
Available
Category:
Pharmacy
Price:
39.90 €
Keywords:
Amlodipine, Olmesartan medoxo, DSC, FTIR.

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