Bookcover of Orphan Receptor
Booktitle:

Orphan Receptor

Betascript Publishing (2011-07-08 )

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ISBN-13:

978-613-6-39260-8

ISBN-10:
6136392607
EAN:
9786136392608
Book language:
English
Blurb/Shorttext:
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. An orphan receptor is an apparent receptor that has a similar structure to other identified receptors but whose endogenous ligand has not yet been identified. If a ligand for an orphan receptor is later discovered, the receptor is referred to as an "adopted orphan". Examples of orphan receptors are found in the G protein-coupled receptor (GPCR) and nuclear receptor families. GPCR orphan receptors are usually given the name "GPR" followed by a number, for example GPR1. If an endogenous ligand is found, the orphan receptor is "adopted". An example is the receptor FXR, which is activated by bile acids. Adopted orphan receptors in the nuclear receptor group include the farnesoid X receptor (FXR), liver X receptor (LXR), and peroxisome proliferator-activated receptor (PPAR).
Publishing house:
Betascript Publishing
Website:
https://www.betascript-publishing.com/
Edited by:
Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow
Number of pages:
132
Published on:
2011-07-08
Stock:
Available
Category:
Biochemistry, biophysics
Price:
45.00 €
Keywords:
Receptor, Endogeny, ligand, G Protein-Coupled Receptor, Receptors, Ligands., G-protein coupled receptor

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