Bookcover of Intricacies of T Cell Activation and Signaling
Booktitle:

Intricacies of T Cell Activation and Signaling

Special Reference to CD8 T Cells

VDM Verlag Dr. Müller (2008-08-28 )

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ISBN-13:

978-3-639-07454-3

ISBN-10:
3639074548
EAN:
9783639074543
Book language:
English
Blurb/Shorttext:
T cell signal transduction is not a linear pathway, but involves multiple components acting as a network. Though CD8 T cells are capable of being stimulated with a brief stimulus, recent studies have brought to focus the persistence of signaling in T cells post synaptic engagement. Though these signals are not strong enough for direct detection, their effect on functional maturity of T cells is ascertained by functional assays. Different outcomes of activated T cells do exhibit a certain level of hierarchy in the order of activation and the strength of signal required for each. The intracellular signaling components seem to form modules involved in persistence of signaling in T cells. This book provides an overview of T cell activation focusing on CD8 T cells.
Publishing house:
VDM Verlag Dr. Müller
Website:
http://www.vdm-verlag.de
By (author) :
FABIAN EBENEZER CHITRA
Number of pages:
104
Published on:
2008-08-28
Stock:
Available
Category:
Biology
Price:
49.00 €
Keywords:
immunology, T cells, signal transduction, T cell activation, immune response

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