Bookcover of Chemical and Biological Investigations of Xylia dolabriformis
Booktitle:

Chemical and Biological Investigations of Xylia dolabriformis

LAP LAMBERT Academic Publishing (2013-05-31 )

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ISBN-13:

978-3-659-37579-8

ISBN-10:
3659375799
EAN:
9783659375798
Book language:
English
Blurb/Shorttext:
Xylia dolabriformis belonging to the Fabaceae family has been investigated for isolation of compounds and evaluation of biological activities as antimicrobial screening and cytotoxicity study. Two compound has been isolated which was identified by extensive analyses of their high resolution NMR (1H-NMR) spectral data.The powdered stem bark of Xylia dolabriformis was extracted with methanol. The concentrated extract was then partitioned with n-Hexane, carbon tetrachloride and chloroform. Chromatographic fractionation and purification of the crude methanolic extract yielded two compounds. The purified compounds identified are stigmasterol and β-Amyrinone. Microbiological investigation showed chloroform soluble fraction has mild to moderate antimicrobial activity. In the brine shrimp lethality bioassay, the crude methanolic extract ,n-Hexane, carbon tetrachloride, chloroform and aqueous soluble fractions, were found to show LC50 15.5 µg/ml, 7.08 µg/ml, 3.89 µg/ml, 3.80 µg/ml & 5.01 µg/ml, respectively. This indicated that carbon tetrachloride & chloroform soluble fractions were highly cytotoxic.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Fataha Nur Robel
Number of pages:
144
Published on:
2013-05-31
Stock:
Available
Category:
Organic chemistry
Price:
61.90 €
Keywords:
chemical, Xylia dolabriformis, Biological

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