Aurora Inhibitor
Cell cycle, Aurora kinase, Cytokinesis, Kinase, Carcinogenesis, Enzyme inhibitor, Tumor, Gene
978-613-9-99245-4
6139992451
68
2011-12-06
245.34 HK$
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Aurora kinases regulate cell cycle transit from G2 through cytokinesis and, thus, are targets in cancer therapy. There are three mammalian aurora kinase genes, encoding aurora A, B and C. Intense investigation has focused on aurora A and B as they appear to play a role in oncogenesis with aurora A identified as a low penetrance tumor susceptibility gene in mice and humans. Aurora kinases could be potential targets for novel small-molecule enzyme inhibitors.
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