Couverture de Pyrrolo-benzodiazepine class of Privileged Medicinal Scaffolds
Titre du livre:

Pyrrolo-benzodiazepine class of Privileged Medicinal Scaffolds

Synthesis of Pyrrolo benzodiazepine as anti-canccer agents

LAP LAMBERT Academic Publishing (02-08-2011 )

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ISBN-13:

978-3-8454-2151-3

ISBN-10:
3845421517
EAN:
9783845421513
Langue du livre:
Anglais
texte du rabat:
On account of the wide range of the biological properties displayed by benzodiazepine derived compounds, benzodiazepine scaffold have been considered among the most important privileged structures for drug discovery. The development of novel biological materials based on the privileged structure is an intense area of research. Global efforts are underway to develop chemotherapeutic agentsThe main thrust of work in the area of additional fused heterocyclic rings is stimulated by the isolation of a series of antitumor antibiotics such as anthramycin, sibiromycin, tomaymycin, prothacarin, chicamycins A,B and neothramycins A,B (to mention a few), from the pyrrolo[2,1-c][1,4]-benzodiazepine class of compounds These biosynthetically derived materials are well known for inhibiting DNA replication on account of the formation of DNA – antibiotic adduct .
Maison d'édition:
LAP LAMBERT Academic Publishing
Site Web:
https://www.lap-publishing.com/
de (auteur) :
Sumitra Nain, Prof. D. Kishore, Prof. B. P. Nagori
Numéro de pages:
76
Publié le:
02-08-2011
Stock:
Disponible
Catégorie:
Pharmacie
Prix:
49.00 €
Mots-clés:
Pyrrolo benzodiazepine, anti-canccer agents

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