Couverture de Impact Of Tel-aml-1 Fusion Gene On All Patients In Basrah, Iraq
Titre du livre:

Impact Of Tel-aml-1 Fusion Gene On All Patients In Basrah, Iraq

Relation of TEL-AML1 fusion gene with p53 mutation and HPV B19 on newly diagnosed acute lymphoblastic patients in Basrah

LAP LAMBERT Academic Publishing (08-10-2012 )

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ISBN-13:

978-3-659-16021-9

ISBN-10:
3659160210
EAN:
9783659160219
Langue du livre:
Anglais
texte du rabat:
Acute lymphoblastic leukemia (ALL) is the most common type of childhood malignancy. Dramatic advances in its treatment over the past three decades have changed it from a universal fatal to an almost curable disease in 75% of cases. However significant challenges remain including developing better methods to predict which patients can be cured with less toxic treatment and which ones will benefit from augmented therapy . In addition, 25% of patients fail therapy and novel treatments that are focused on undermining specifically the leukemic process are needed urgently and considered the first step towards preventing this devastating childhood cancer . Developments in Chromosomal abnormalities in childhood ALL had important significance related to diagnosis, management and prognosis. Several clinical studies have shown that chromosome aberration in ALL can be used for risk group classification i.e. classify patients into those who require more-intensive therapy. For instance t(9;22) and 11q23 aberration such as t(4;11) are associated with poor prognosis in ALL, where as t(12;21) is associated with good prognosis.
Maison d'édition:
LAP LAMBERT Academic Publishing
Site Web:
https://www.lap-publishing.com/
de (auteur) :
Wijdan Nazar, Hassan Hassony, Janan Hassan
Numéro de pages:
152
Publié le:
08-10-2012
Stock:
Disponible
Catégorie:
Autres
Prix:
59.00 €
Mots-clés:
childhood acute lymphoblastic leukemia, Human Parvovirus B19., TEL-AML FUSION, P53 mutation

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