Glucuronosyltransferase
Uridine diphosphate, Glycosyltransferase, Catalysis, Glycosyl, Glucuronidation, Drug metabolism
978-620-0-05333-6
6200053332
64
2013-01-10
29.00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UGT) is a glycosyltransferase that catalyzes addition of the glycosyl group from a UTP-sugar to a small hydrophobic molecule. This is glucuronidation reaction. Alternative names: glucuronyltransferase, UDP-glucuronyl transferase, UDP-GT. Glucuronosyltransferases are responsible for the process of glucuronidation, a major part of phase II metabolism. Arguably the most important of the Phase II (conjugative) enzymes, UGTs have been the subject of increasing scientific inquiry since the mid-to-late 1990s.
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