Arylsulfatase B
Enzyme, Maroteaux–Lamy syndrome, Arylsulfatase, Glycosaminoglycan, Dermatan sulfate, Chondroitin sulfate
978-620-0-19816-7
6200198160
84
2013-01-10
34.00 €
eng
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Arylsulfatase B (ARSB) is an enzyme associated with mucopolysaccharidosis VI. Arylsulfatase B is among a group of arylsulfatase enzymes present in the lysosomes of the liver, pancreas, and kidneys of animals. The purpose of the enzyme is to hydrolyze sulfates in the body. ARSB does this by breaking down Glycosaminoglycans(GAGs), which are large sugar molecules in the body. ARSB targets two GAGs in particular: dermatan sulfate and chondroitin sulfate. Over 130 mutations to ARSB have been found, each leading to a deficiency in the body. In most cases, the mutation occurs on a single nucleotide in the sequence.
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