Homology Modeling of Human NK-1 Receptor and Docking Study
Structure Based Drug Design
978-3-659-80420-5
3659804207
92
2015-11-16
54.90 €
eng
https://images.our-assets.com/cover/230x230/9783659804205.jpg
https://images.our-assets.com/fullcover/230x230/9783659804205.jpg
https://images.our-assets.com/cover/2000x/9783659804205.jpg
https://images.our-assets.com/fullcover/2000x/9783659804205.jpg
Neurokinin-1 (NK-1) receptor regulates many biological functions related to cancer, such as tumor cell proliferation, angiogenesis and migration of tumor cells for invasion and metastasis. The NK-1 receptor antagonists specifically inhibit tumor cell proliferation, migration of the tumor cells and show antiangiogenic effect. Therefore, the development of NK-1 antagonists for the treatment of cancer is of current interest. The 3D structure of NK-1 is not available from protein data bank. This hampers the design of selective NK-1 antagonists. This book describes the homology modeling of the human NK-1 receptor using multiple templates to provide structural basis for the design of new NK-1 inhibitors and anticancer agents. The authors anticipate that the book will be very useful for the researchers who are working on the design and development of NK-1 receptor antagonists and anticancer agents.
https://www.morebooks.de/books/es/published_by/lap-lambert-academic-publishing/47/products
Farmacia
https://www.morebooks.de/store/es/book/homology-modeling-of-human-nk-1-receptor-and-docking-study/isbn/978-3-659-80420-5