Portada del libro de Design Development and In vitro characterisation of Dofetilide tablets
Título del libro:

Design Development and In vitro characterisation of Dofetilide tablets

Based on Pulsatile Drug Delivery System

LAP LAMBERT Academic Publishing (2017-11-27 )

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ISBN-13:

978-620-2-07988-4

ISBN-10:
6202079886
EAN:
9786202079884
Idioma del libro:
Inglés
Notas y citas / Texto breve:
The purpose of the book is to develop and characterize pulsatile drug delivery system of a novel drug Dofetilide. Initially the core tablets were prepared by using various concentrations of super disintegrates, the formulated core tablets were coated with the polymers by using compression coating technology. Sodium starch glycollate, cross povidone and cross carmellose sodium were the super disintegrants used in core tablet formulation. All the core and press coated tablet formulations were subjected to various physical and chemical evaluation tests for core and press coated tablets. The thickness, hardness and weight variation shown by all the tablet formulations were found within the official pharmacopoeial limits. The compression coating was done by using Eudragit S 100, Eudragit L 100 and ethyl cellulose as coating polymers. The maximum drug release data obtained by using combination of polymers in the ratio of 1:1. This book definitely will be useful for the researchers who wish to design and fabricate pulsatile drug delivery system for better therapeutic outcome.
Editorial:
LAP LAMBERT Academic Publishing
Sitio web:
https://www.lap-publishing.com/
Por (autor):
Sajal Kumar Jha, Uday Kumar Gore
Número de páginas:
80
Publicado en:
2017-11-27
Stock:
Disponible
Categoría:
Farmacia
Precio:
35.90 €
Palabras clave:
Compression Coating, Dftd, Super disintegrates, Pulsatile tablets.

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