Buchcover von Design & Evaluation of Controlled Release Matrix Tablets of Prazosin
Buchtitel:

Design & Evaluation of Controlled Release Matrix Tablets of Prazosin

Modern Management of Hypertension

LAP LAMBERT Academic Publishing (03.04.2018 )

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ISBN-13:

978-613-8-38782-4

ISBN-10:
6138387821
EAN:
9786138387824
Buchsprache:
Englisch
Klappentext:
In the present study, we have prepared matrix tablet formulations using Prazocin as a model drug and Ethyl Cellulose, Two grades of Hydroxy Propyl Methyl Cellulose- HPMC-K4M & HPMC-K100M as polymers in different ratios. The developed matrix tablets were evaluated for different physical-chemical evaluations like drug content, hardness, friability, swelling index etc. All the formulations had shown the results within prescribed limits. The In vitro drug release study indicates that formulation PCF-7 containing EC, HPMC K100M in 1:2 ratio shown good release pattern for 14 hours compares to other formulations. The short-term stability study proved no change in the formulation of ageing and it indicates good stability.
Verlag:
LAP LAMBERT Academic Publishing
Webseite:
https://www.lap-publishing.com/
von (Autor):
Rajan Kothari, Gaurav Kumar Sharma, Pankaj Chasta Atul Tiwari
Seitenanzahl:
76
Veröffentlicht am:
03.04.2018
Lagerbestand:
Lieferbar
Kategorie:
Pharmazie
Preis:
35,90 €
Stichworte:
Ethyl Cellulose, Matrix Tablets, Prazosin, HPMC-K4M & K100M.

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