Extent of HIV-1 drug resistance among drug naive populations of Kenya的封面
书籍主题:

Extent of HIV-1 drug resistance among drug naive populations of Kenya

HIV drug resistance among drug naive populations

VDM Verlag Dr. Müller (2010-04-09 )

Books loader

Omni badge 有获得代金券的资格
ISBN-13:

978-3-639-24288-1

ISBN-10:
3639242882
EAN:
9783639242881
书籍语言:
英文
作品简介:
Background: Development of resistance to antiretroviral medication can occur in persons on antiretroviral therapy, acquisition of already resistant strain in persons who have never taken medication or by natural polymorphism of the virus in vivo. This leads to treatment failure hence complicating management of HIV patients. Objectives: To determined the extent of HIV-1 drug resistance mutations in HIV-1 positive drug naïve persons in Kenyan population. Methods: HIV-1 positive plasma samples from seventy-eight (78) drug naïve subjects were collected from Health Centers in five provinces in Kenya. HIV-1 viral RNA was extracted using Qiagen® RNA isolation kit and a 697bp size portion of HIV-1 reverse transcriptase (RT) gene amplified by nested PCR using specific primers and amplified products analyzed by gel electrophoresis and visualized under UV light. The successfully amplified products were directly sequenced using the Big Dye® sequence terminator technology (Applied Biosystems®).Generated sequences were then compared with reference HIVdrug resistance database (http://hivdb.stanford.edu/).
出版社 :
VDM Verlag Dr. Müller
网址:
http://www.vdm-verlag.de
由(作者):
Anthony Nyamache
页码 :
152
发表日期:
2010-04-09
现货:
备有现货
类别:
临床学科
价格:
59.00 €
关键词:
HIV, genotyping, drug resistance, sequencing, Kenya, RT region

Books loader

时事通讯

Adyen::amex Adyen::mc Adyen::visa Adyen::cup Adyen::unionpay Paypal 银行转帐

LOGIN
  0产品在购物车内
编辑购物车
Loading frontend
LOADING