9783838366043

Antibody-mediated myocarditis

Anita Kuan

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ISBN-13:

978-3-8383-6604-3

ISBN-10:
3838366042
EAN:
9783838366043
Book language:
English
Blurb/Shorttext:
Autoimmune disease occurs when (1) there is a breakdown in self-tolerance and (2) the target organ is susceptible to damage by the immune system. Our studies focus on the susceptibility of the target organ to damage. Autoimmune myocarditis is an inflammatory heart disease characterized by myocyte necrosis and an inflammatory infiltrate in the myocardium. Clinically, the disease can range from a mild illness to a serious condition characterized by heart failure, arrhythmias and in some cases can lead to death. Studies in our laboratory have correlated the presence of myosin, or a myosin-like protein, in the extracellular matrix of the heart to disease susceptibility to antibody-mediated myocarditis. Here, we explore what factors determine susceptibility to antibody-induced cardiac damage.
Publishing house:
LAP LAMBERT Academic Publishing
Website:
https://www.lap-publishing.com/
By (author) :
Anita Kuan
Number of pages:
112
Published on:
2010-06-04
Stock:
Available
Category:
Microbiology
Price:
49.00 €
Keywords:
myocarditis, immunology, Autoimmune Disease, Myosin, Rheumatic Fever, extracellular matrix, Susceptibility, antibody, Immunoglobulin, genetic mapping

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